Clobazam for preventing seizures
This leaflet is for parents and carers about how to use this medicine in children. Our information may differ from that provided by the manufacturers, because their information usually relates to adults. Read this leaflet carefully. Keep it somewhere safe so that you can read it again.
Do not stop giving Clobazam suddenly, as your child may have more seizures.
Name of medicine
Common brands: Fruisium
Why is it important for my child to take Clobazam?
Clobazam is used to prevent epileptic seizures. It is important that your child takes clobazam regularly so that they have fewer seizures. Seizures may also be called convulsions or fits.
What is Clobazam available as?
- Tablets: 10 mg (white and contain lactose), 5 mg tablets can be ordered specially (these may also contain lactose)
- Liquid medicine: this may be ordered specially from your pharmacist but it may take up to 3 weeks to supply
When should I give Clobazam
The Clobazam is usually given twice each day. Give one dose in the morning and one in the evening. Ideally these times are 10–12 hours apart. For example, this could be between 7am and 8am and between 7pm and 8pm.
Your doctor may tell you to start by giving Clobazam once a day until your child gets used to it. This is usually in the evening.
How much should I give?
Your doctor will work out the amount of clobazam (the dose) that is right for your child. The dose will be shown on the medicine label.
When you first start giving clobazam to your child, you will give them a small amount and then increase the dose bit by bit over a few days or weeks. This helps your child to get used to the medicine. Your doctor will explain what to do.
It is important that you follow your doctor’s instructions about how much to give.
How should I give Clobazam?
- Crushed tablets can also be mixed into 5 -10 mL of water (one or two spoons) in a small glass. Make sure your child takes it straight away. You can use an oral syringe to give the mixture to your child.
- Tablets should be swallowed with a glass of water, squash or juice. Your child should not chew the tablets.
- You can crush the tablet and mix it with a small amount of soft food such as yogurt, honey, or mashed potato. Make sure your child swallows it straight away, without chewing.
- Shake the medicine well.
- Measure out the right amount using an oral syringe or a medicine spoon. You can get these from your pharmacist. Do not use a kitchen teaspoon as it will not give the right amount.
When should the medicine start working?
It may take a few days or even weeks for Clobazam to work properly, so your child may still have their symptoms for a while. This is because the amount of medicine has to be increased slowly. Continue to give the medicine as you have been told to by your doctor.
What if my child is sick (vomits)?
- If your child is sick less than 30 minutes after having a dose of Clobazam, give them the same dose again.
- If your child is sick more than 30 minutes after having a dose of Clobazam, do not give them another dose. Wait until the next normal dose.
If your child is sick again, seek advice from your family doctor, nurse, pharmacist, or hospital. They will decide what to do based on your child’s condition and the specific medicine involved.
What if I forget to give it?
If you remember up to 4 hours after you should have given a dose, give your child the missed dose.
For example, if you usually give a dose at about 7 am, you can give the missed dose at any time up to 11 am. If you remember after that time, do not give the missed dose. Wait until the next normal dose. You do not need to wake up a sleeping child to give a missed dose.
Never give a double dose of Clobazam.
What if I give too much?
If you think you may have given your child too much Clobazam, contact your doctor or local NHS services (details at end of leaflet) or take your child to hospital. Have the medicine container or packaging with you, even if it is empty. This will be useful to the doctor.
Are there any possible side effects?
We use medicines to make our children better, but sometimes they cause effects that we don’t want (side-effects).
Clobazam usually causes only mild side-effects, which should get better as your child’s body gets used to the medicine.
- Your child may be drowsy (sleepy), have little energy, or have difficult with coordination or balance. They may also be aggressive or easily irritated. These effects should get better after about a week. If they don’t, contact your doctor.
- A few children get a mild tremor (shakiness) of their fingers. This should get better after 2–3 weeks. If it doesn’t, contact your doctor.
Can other medicines be given at the same time as Clobazam?
- You can give your child medicines that contain paracetamol or ibuprofen, unless your doctor has told you not to.
- Check with your doctor or pharmacist before giving any other medicines to your child. This includes herbal and complementary medicines.
Epilepsy and pregnancy
- Pregnancy presents a risk to both the mother with epilepsy and her unborn baby. If your daughter has sex, it is essential that she uses adequate contraception to prevent an unplanned pregnancy.
- If your daughter thinks she may be pregnant, it is important that she sees her doctor as soon as possible. Your daughter should keep taking her medication until she sees her doctor.
Clobazam and pregnancy
- Clobazam may harm an unborn baby.
- The oral contraeptive pill can be used safely by women or girls who are taking clobazam.
Is there anything else I need to know about this medicine?
Do not suddenly stop giving Clobazam to your child, as they may have a seizure. If you are worried, contact your doctor but carry on giving the medicine to your child as usual.
If your child seems to have more seizures than usual, contact your doctor or epilepsy nurse.
- You may find that clobazam starts to work less well when your child has been taking it for several months, or even after a year, and they may start to have more seizures. If this happens, contact your doctor.
- Some girls have seizures only around the time of their period. In this case, the hospital doctor may suggest that your daughter starts taking clobazam when her period is due, and continues for 5–7 days, depending on how long it lasts. She should take it twice a day (morning and evening).
General advice about medicines
Advice about medicines for seizures
- If your doctor decides to stop a particular medicine, they will discuss this with you. They will usually reduce the dose bit by bit.
- It is best that your child always has the same brand of each medicine, as there may be differences between brands. Keep a record of which medicines your child has.
- Try to give medicines at about the same times each day, to help you remember.
- Only give this medicine to your child. Never give it to anyone else, even if their condition appears to be the same, as this could do harm.
- Make sure that you always have enough medicine. Order a new prescription at least 2 weeks before you will run out.
- Make sure that the medicines you have at home have not reached the ‘best before’ or ‘use by’ date on the packaging. Give old medicines to your pharmacist to dispose of.
Do not change the dose of any medicine without talking to your doctor first.
If you think someone else may have taken the medicine by accident, contact your doctor straight away.
Where should I keep this medicine?
- Keep the medicine in a cupboard, away from heat and direct sunlight.
- It does not need to be kept in the fridge.
- Make sure that children cannot see or reach the medicine.
- Keep the medicine in the container it came in.
Who to contact for more information?
Your child’s doctor, pharmacist or nurse will be able to give you more information about Clobazam and about other medicines used to treat epilepsy.
England: NHS 111
Scotland: NHS 24
Northern Ireland: NI Direct
Wales: NHS 111 Wales
0808 800 5050www.epilepsy.org.uk
01494 601 400epilepsysociety.org.uk
Version . © NPPG, RCPCH and WellChild, all rights reserved. Review by February 2011.
The primary source for the information in this leaflet is the British National Formulary for Children. For details on any other sources used for this leaflet, please contact us through our website, www.medicinesforchildren.org.uk.
We take great care to make sure that the information in this leaflet is correct and up-to-date. However, medicines can be used in different ways for different patients. It is important that you ask the advice of your doctor or pharmacist if you are not sure about something. This leaflet is about the use of these medicines in the UK, and may not apply to other countries. The Royal College of Paediatrics and Child Health (RCPCH), the Neonatal and Paediatric Pharmacists Group (NPPG), WellChild and the contributors and editors cannot be held responsible for the accuracy of information, omissions of information, or any actions that may be taken as a consequence of reading this leaflet.